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Case Report: COVID-19 and Chagas Disease in Two Coinfected Patients.
Alberca, Ricardo Wesley; Yendo, Tatiana Mina; Leuzzi Ramos, Yasmim Álefe; Fernandes, Iara Grigoletto; Oliveira, Luana de Mendonça; Teixeira, Franciane Mouradian Emidio; Beserra, Danielle Rosa; de Oliveira, Emily Araujo; Gozzi-Silva, Sarah Cristina; Andrade, Milena Mary de Souza; Branco, Anna Cláudia Calvielli Castelo; Pietrobon, Anna Julia; Pereira, Nátalli Zanete; de Brito, Cyro Alves; Orfali, Raquel Leão; Aoki, Valéria; Duarte, Alberto José da Silva; Benard, Gil; Sato, Maria Notomi.
Am J Trop Med Hyg ; 103(6): 2353-2356, 2020 Dec.
Article in English | MEDLINE | ID: covidwho-1005552

ABSTRACT

American trypanosomiasis, also named Chagas disease (CD), is an anthropozoonosis caused by the protozoan parasite Trypanosoma cruzi. The disease affects millions of people worldwide, leading yearly to approximately 50,000 deaths. COVID-19, generated by SARS-CoV-2, can lead to lymphopenia and death. We hereby describe the first report of two patients with CD and COVID-19 coinfection, from hospitalization until patients' death.


Subject(s)
COVID-19/diagnosis , Chagas Cardiomyopathy/diagnosis , RNA, Viral/genetics , SARS-CoV-2/pathogenicity , Trypanosoma cruzi/pathogenicity , Aged , Brazil , COVID-19/parasitology , COVID-19/pathology , COVID-19/virology , COVID-19 Testing/methods , Chagas Cardiomyopathy/parasitology , Chagas Cardiomyopathy/pathology , Chagas Cardiomyopathy/virology , Coinfection , Disease Progression , Fatal Outcome , Female , Hospitalization , Humans , Male , Pacemaker, Artificial , SARS-CoV-2/genetics , Tomography, X-Ray Computed , Trypanosoma cruzi/genetics
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